Solvation model dependency of helix-coil transition in polyalanine.
نویسندگان
چکیده
Helix-coil transitions in polyalanine molecules of length 10 are studied by multi-canonical Monte Carlo simulations. The solvation effects are included by either a distance-dependent dielectric permittivity or by a term that is proportional to the solvent-accessible surface area of the peptide. We found a strong dependence of the characteristics of the helix-coil transition from the details of the solvation model.
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ورودعنوان ژورنال:
- Biophysical journal
دوره 82 6 شماره
صفحات -
تاریخ انتشار 2002